The diabesity epidemic in the light of evolution: insights from the capacity–load model | Jonathan C. K. Wells | Diabetologia

The global nutrition transition, which embraces major changes in how food is produced, distributed and consumed, is associated with rapid increases in the prevalence of obesity, but the implications for diabetes differ between populations. A simple conceptual model treats diabetes risk as the function of two interacting traits: ‘metabolic capacity,’ which promotes glucose homeostasis, and ‘metabolic load’, which challenges glucose homoeostasis. Population variability in diabetes prevalence is consistent with this conceptual model, indicating that the effect of obesity varies by ethnicity. Evolutionary life history theory can help explain why variability in metabolic capacity and metabolic load emerges. At the species level (hominin evolution), across human populations and within individual life courses, phenotypic variability emerges under selective pressure to maximise reproductive fitness rather than metabolic health. Those exposed to adverse environments may express or develop several metabolic traits that are individually beneficial for reproductive fitness, but which cumulatively increase diabetes risk. Public health interventions can help promote metabolic capacity, but there are limits to the benefits that can emerge within a single generation. This means that efforts to curb metabolic load (obesity, unhealthy lifestyles) must remain at the forefront of diabetes prevention. Such efforts should go beyond individuals and target the broader food system and socioeconomic factors, in order to maximise their efficacy.

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This article surprisingly reveals the existence of a very precise spiral rhythm in the emergence of the evolutionary leaps that mark the history of the universe.

The proposed hypothesis is very simple: just as in any musical instrument successive second harmonics (1/3 of the vibrating unit) progressively generate new sounds; these same second harmonics generate all the major evolutionary novelties in universal dynamics as a whole. It is truly surprising that such a simple proposal is found to be precise and categorical when cross-checked against historical data. Let us see.

Fitting our ‘periodic table’ of rhythms to the date of the appearance of matter –the Big Bang– and of organic life, we see that every single instant of the emergence of successive taxonomic degrees of human phylogeny is marked out with utter precision: Kingdom: animal, Phylum: chordata, Class: mammal, Order: primate, Superfamily: hominoid, Family: hominid and Genus: homo! The same then occurs with all the stages of maturation of our primitive ancestors: H. habilis, H. erectus, archaic H. sapiens, H. sapiens and H. sapiens sapiens! Once more, the precision of our hypothesis is repeated in the successive transformations that humanity has experienced in its more recent history: the Neolithic, Antiquity, the Middle Ages, the Modern Age and the emergentPostmodern Age! If, as we see it, all these stages resoundingly fit the provisions of the ‘periodic table’ of rhythms that we have proposed, it is more than likely that our hypothesis may also provide the key to glimpse the successive phases yet to be deployed in the years to come in an ever-accelerating process that will eventually lead to a moment of infinite creativity –Omega– within a couple of centuries.

All this is, indeed, unexpected and surprising, but is now almost certain when we verify that the same hypothesis that has behaved with utter precision when applied to the process of global evolution, also does so when cross-checked against the process of development of the individual human being! Within the same time frame, with the same pattern of folding and unfolding, and passing through the same stages, our ‘periodic table’ of rhythms periodically marks out –step by step– the successive phases embryologists, developmental psychologists and spiritual teachers talk of, thus confirming the old idea of phylogenetic-ontogenetic parallelism and pointing very specifically to an astonishing fractal and holographic universe.

It is impossible, absolutely impossible, that all this accumulation of linked “coincidences” –in both the field of overall development and that of individual human development– highlighted in this paper is the product of mere chance. The conclusions that emerge from all this clash head on with many assumptions of predominant materialistic science. Our proposal, which provides a better fit to the presented data, points to the non-duality of energy and consciousness, as posed by many traditions of wisdom. From these pages, we invite all our readers to participate in this emerging experiential and theoretical research in which dazzling prospects can be glimpsed.

Keywords: Crisis darwinism, integral paradigm, alternative hypothesis, divergent-convergent spiral evolution, accelerated rhythm, teleology, singularity, omega point, syntropy, musical harmonics, stationary waves, quantum leaps, evolutive discontinuity, fractal time, holographic universe, big history, macrocosmos (paleontology, anthropology, history), microcosmos (embriology, psychology), ontogeny-philogeny, spectrum energy-consciousness, spiral dynamics, chakras, perennial philosophy, non-duality.

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