Living systems sustain themselves through coherence — the dynamic alignment of structure, physiological state, interpretation, and meaning across time. This white paper outlines a unified framework for understanding how coherence is generated and lost across scales, beginning with the embodied nervous system (proprioception, interoception, and exteroception), extending through relationships and co-regulation, into communities and culture, and upward into institutional design, economic provisioning systems, and planetary ecological stability. Integrating neuroscience, developmental psychology, trauma research, complexity science, regenerative systems theory, and John McMurtry’s life-value onto-axiology, the paper shows that coherence breakdown across these scales follows the same predictable patterns of hypervigilance, collapse, and fragmentation — each reflecting adaptive responses to conditions of constraint and instability. In place of fragmented interventions, we propose a cross-scale regenerative sequencing principle: Support Form → Regulate State → Restore Shared World → Rebuild Meaning. This framework provides a practical basis for redesigning healthcare, education, governance, economic systems, and ecological stewardship toward the sustained flourishing of life.
