The Tubular Architecture of Coherence: Nested Bio-Waveguides and the Maintenance of Multiscale Biological Order | ChatGPT5 & NotebookLM

Life maintains ordered structure and function despite constant molecular motion and thermodynamic noise. This continuity cannot be explained by chemical reactions alone. Biological systems sustain coherence through a nested architecture of tubular and helical waveguides — including DNA, protein helices, microtubules, cytoskeletal networks, membranes, mitochondrial cristae, collagen fibrils, and the fascial continuum — that enable mechanical, electrical, and protonic oscillations to propagate with stability across spatial and temporal scales.

This paper articulates a unified framework in which coherence emerges from phase-stabilized resonance supported by geometry and hydration. We describe how membrane potential, mitochondrial redox oscillations, cytoskeletal alignment, and fascial load-bearing continuity form a coherence cascade that integrates molecular identity, cellular organization, tissue integrity, physiological rhythm, and embodied perception. We show how aging, chronic inflammation, cancer, autoimmune dysregulation, and trauma physiology can be understood as loss of re-entrainment capacity, and how healing and regeneration occur when phase stability is restored.

The model yields testable experimental predictions and provides mechanistic grounding for clinical, somatic, and regenerative practices. Coherence is presented not as metaphor, but as a physically measurable and therapeutically modifiable property of living systems.

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