This white paper explores the Heart Sutra, a core Mahāyāna Buddhist text, not only as a profound spiritual teaching but as a conceptual Rosetta Stone for contemporary science and regenerative social transformation. We integrate its central doctrine of śūnyatā (emptiness) with developments in quantum physics, systems theory, biosemiotics, and complexity science, arguing that it prefigures a paradigm of interdependence, emergence, and coherence. We then trace the implications of this ontology into domains of ecological governance, regenerative economics, and compassionate policy design. The Heart Sutra’s vision of nonduality, liberation, and interbeing provides a moral and metaphysical compass for evolving human civilization beyond fragmentation, domination, and alienation — toward a living society grounded in coherence, compassion, and relational flourishing.
