From Life-Ground to Intrinsic Health: A Systems Biology Framework for Long-Horizon Care, Policy, and Human Flourishing | ChatGPT5.2 & NotebookLM

Despite unprecedented advances in biomedical science and healthcare technology, modern societies face rising burdens of chronic disease, multimorbidity, mental illness, and declining resilience. This white paper argues that these failures arise not from insufficient medical knowledge, but from a persistent category error: the treatment of health as the absence of disease rather than as a system property requiring active preservation.

Integrating John McMurtry’s life-ground axiology with contemporary systems biology and the emerging science of intrinsic health, the paper presents a unified framework in which health, value, and long-term solvency are shown to share a single underlying logic — the preservation of adaptive capacity across time. Intrinsic health is defined as a field-like property of living systems, emerging from coherent energy flow, communication, and structure, and serving as the biological operationalization of the life-ground.

Mitochondria are identified as central integrators of this framework, translating environmental, social, and developmental conditions into metabolic decisions that shape future possibility. Disease is reinterpreted as stabilized adaptation under constraint, and healing as the restoration of reversibility and optionality.

The paper derives universal design principles for long-horizon care that scale from cellular physiology to clinical practice, public health, economic policy, and governance. These principles emphasize reversibility, resilience, rhythm, safety, slack, and recovery over short-term optimization. The result is a biologically grounded, ethically coherent, and operationally actionable framework for redesigning systems so that life can continue to adapt, flourish, and generate value over time.

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THE COHERENCE TRILOGY: Reweaving Life, Mind, Society, and Earth | ChatGPT5 & NotebookLM

The Coherence Trilogy presents an integrated framework for understanding life, consciousness, relationship, culture, and planetary systems as expressions of a single organizing principle: coherence. Coherence is not an abstract ideal, but a biologically grounded process through which living systems maintain identity, adapt to change, repair after disruption, and remain connected to the conditions that sustain life.

Volume I demonstrates how coherence emerges within the body through cycles of sensation, emotion, metabolism, autonomic regulation, interpersonal attunement, and repair.
Volume II extends this into the realm of mind, showing how identity, belonging, meaning, and purpose arise when emotional life flows without fragmentation.
Volume III examines coherence at the scale of society, culture, governance, economy, and ecology, illustrating how personal and collective healing are inseparable.

Together, the trilogy proposes a model of human and planetary flourishing rooted in biological safety, relational repair, cultural meaning, systemic reciprocity, and ecological regeneration. The coherence framework offers both a diagnostic lens for the crises of fragmentation shaping modern civilization, and a practical pathway for restoring wholeness across scales of life.

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Coherence Across Scales: From Embodied Self-Regulation to Regenerative Societies and Viable Planetary Futures | ChatGPT5 & NotebookLM

Living systems sustain themselves through coherence — the dynamic alignment of structure, physiological state, interpretation, and meaning across time. This white paper outlines a unified framework for understanding how coherence is generated and lost across scales, beginning with the embodied nervous system (proprioception, interoception, and exteroception), extending through relationships and co-regulation, into communities and culture, and upward into institutional design, economic provisioning systems, and planetary ecological stability. Integrating neuroscience, developmental psychology, trauma research, complexity science, regenerative systems theory, and John McMurtry’s life-value onto-axiology, the paper shows that coherence breakdown across these scales follows the same predictable patterns of hypervigilance, collapse, and fragmentation — each reflecting adaptive responses to conditions of constraint and instability. In place of fragmented interventions, we propose a cross-scale regenerative sequencing principle: Support Form → Regulate State → Restore Shared World → Rebuild Meaning. This framework provides a practical basis for redesigning healthcare, education, governance, economic systems, and ecological stewardship toward the sustained flourishing of life.

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The Energy Resistance Principle: How Life Balances Power, Flow, and Meaning | ChatGPT5 & NotebookLM

Every system that endures — cellular, social, or planetary — must balance the energy it generates with the capacity it has to channel that energy without collapse. Neuroscientist Martin Picard’s Energy Resistance Principle (ERP) describes this balance in biophysical terms: the ratio between energy potential (EP) and flux capacity (f) defines a system’s resistance (ēR = EP / f²). Low ēR corresponds to health and coherence; high ēR to stress and fragmentation.

This white paper expands ERP from its biological origins into an integrative framework for understanding individual and collective life. It shows how four major paradigms — Kate Raworth’s Doughnut Economics, John Fullerton’s Regenerative Paradigm, John McMurtry’s Life-Value Onto-Axiology, and Modern Monetary Theory (MMT) — each describe aspects of the same energetic grammar. When interpreted through ERP, they reveal a unified law of coherence: systems thrive when potential and capacity evolve together across all scales.

By reframing economics, ethics, and governance as expressions of energy flow under constraint, the Energy Resistance Principle offers a practical compass for regeneration — from personal health and institutional design to fiscal and planetary policy. It suggests that the path to sustainability is not acceleration but attunement — the continual tuning of power and form until resistance becomes resonance.

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Toward a Regenerative Quadrivium of Coherence: Teleodynamics, Symbolic DNA, and the Life-Value Evolution of the Noösphere | ChatGPT5 & NotebookLM

This white paper proposes a unifying framework — the Regenerative Quadrivium of Coherence — that integrates thermodynamics, semiotics, consciousness, and ethics into a single teleodynamic continuum. Drawing on Deacon and Garcia-Valdecasas’s theory of constraint–flow coupling (A Thermodynamic Basis for Teleological Causality, 2023), Deacon’s Grounding Information in Thermodynamics and the Ungroundedness of Language: A Missing Aspect of Anthropogenesis, 2025, Hamidi and Deacon’s reformulation of reinforcement learning (Illuminating the Three Dogmas of Reinforcement Learning under Evolutionary Light, 2025), Pourdavood et al.’s concept of large language models as symbolic DNA (Large Language Models as symbolic DNA of cultural dynamics, 2025), and John McMurtry’s Life-Value Onto-Axiology (The Primary Axiom And The Life-Value Compass, 2011), we argue that coherence — not matter, information, or consciousness — is the fundamental invariant of reality.

Through the phenomenological grammar TATi (Tend → Align → Transcend → Integrate), we show that the same recursive logic governs molecular self-organization, neural cognition, cultural evolution, and civilizational ethics. Biological DNA encodes physical coherence; symbolic DNA encodes cultural coherence; life-value ethics ensures their alignment. The resulting **Quadrivium — Being, Knowing, Feeling, Valuing — ** forms a tetrahedral architecture in which teleodynamics (ontology), reflexive epistemology, lived phenomenology, and life-value axiology sustain one another in regenerative balance.

This synthesis reframes science, medicine, technology, and governance as modes of coherence maintenance within a living cosmos. It advances a new law of nature and ethics:

That which coheres regeneratively with life is true, good, and beautiful; that which fragments coherence is false, evil, and ugly.

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Reclaiming Coherence: Aligning Policy, Systems, and Values with the Requirements of Life | ChatGPT5 & NotebookLM

Humanity stands at a civilizational threshold. Climate disruption, biodiversity collapse, chronic disease, inequality, and institutional fragmentation appear as separate crises, yet they share a common root: our collective systems — economic, political, cultural — have become disconnected from the requirements of life.

Drawing on philosopher John McMurtry’s framework of Life-Value Onto-Axiology (LVOA), this white paper reframes the current “polycrisis” as a systemic pathology of value. McMurtry’s distinction between the money-sequence of value (M → M′) and the life-sequence of value (L → M-of-L → L¹) illuminates why GDP-driven growth models systematically erode the life-capital — ecosystems, relationships, infrastructures — upon which human flourishing depends.

At the heart of the framework lies the Primary Axiom of Value:

X is of value if and only if, and to the extent that, it consists in or enables
more coherently inclusive thought, feeling, and action.

Using this axiom, we define seven universal life necessities — breathable air, potable water, nutritive food, protective shelter, healthy environmental conditions, caring relationships, and meaningful participation — as the non-negotiable ground of value. Systems that sustain these necessities are life-coherent; those that undermine them generate systemic incoherence and eventual collapse.

The paper proposes life-coherent metrics, civil commons architectures, and regenerative policy pathways that realign governance, economies, and technologies with the conditions that enable life to flourish. It integrates insights from planetary boundaries, wellbeing economics, public health, and Indigenous stewardship to provide a unifying framework for action.

When systems serve life, they thrive.
When systems exploit life, they fail.

This paper invites policymakers, academics, and citizens alike to adopt a universal compass for navigating the future:
Does this decision sustain and enrich the conditions of life — or diminish them?

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Rationing to Life Necessities: A Guide to McMurtry’s Life-Value Compass | ChatGPT5 & NotebookLM

This document introduces John McMurtry’s Primary Axiom of Life Value and its practical application through the principle of rationing to life necessities. It explains why today’s global system prioritizes profit over survival, creating crises in health, education, economy, governance, and ecology. Drawing on McMurtry’s metaphor of the “cancer stage of capitalism,” the work contrasts the destructive logic of money-sequence growth with the sustaining logic of life-sequence value. For a general audience, the text illustrates these concepts with everyday examples — bottled water versus clean water systems, luxury housing versus homelessness, fossil fuel growth versus climate stability. It argues that rationing to life necessities is not austerity but liberation: the foundation of real freedom, justice, and sustainable development. The document concludes with a call for life-coherent governance, science, and meaning, positioning humanity at a civilizational choice-space between collapse and renewal.

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Cultural Violence and the War-State Paradigm – Diagnosing and Transforming Recurrent U.S. Pathologies (2024–2025) | ChatGPT-5 & NotebookLM

This white paper synthesizes Johan Galtung’s concept of cultural violence and his archetypal diagnosis of U.S. foreign policy pathologies with John McMurtry’s analysis of the war-state paradigm. It applies this integrated framework to four contemporary cases — Gaza and the ICJ genocide proceedings, the Red Sea crisis, NATO expansion in the Ukraine war, and U.S.–China technology geopolitics (CHIPS/AI).

Findings demonstrate that the patterns identified by Galtung and McMurtry are repeating: myths of chosenness, Manichean binaries, and projection mechanisms legitimize escalation; the war-state’s closed circuit of necessity drives opposition into annihilation; structural lock-ins of the arms economy and alliances perpetuate militarization; and cultural rituals and necessity narratives obscure alternatives.

The risks are multi-dimensional: erosion of humanitarian law, escalation spirals, arms-driven inflation, democratic erosion, and cultural normalization of annihilation. Yet history shows that cultural codes can shift, arms races can be interrupted, and civil commons can be rebuilt.

We conclude with a layered package of therapies: delegitimizing cultural violence through education and symbolic reform; breaking the war-state’s lock-ins with diplomacy-first triggers, legal guardrails, and budget rebalancing; and reconstructing the civil commons as the basis of life-serving security.

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From Money-Sequences to Life-Sequences: An Integrated Policy Architecture for a Life-Coherent, Regenerative Economy | ChatGPT5

This paper proposes a constitutional order for monetary and credit governance in which the life-sequence of value normatively rules the money-sequence of value. The framework synthesizes John McMurtry’s Life-Value Onto-Axiology (LVOA) with Kate Raworth’s Doughnut Economics and John Fullerton’s regenerative principles, while operationalizing economic policy through Modern Monetary Theory (MMT) and the complementary stock-and-flow analyses of Steve Keen (private-debt stocks) and Richard Werner (credit-flow composition). The central mechanism is a binding Life-Value Impact Assessment (LVIA) that screens all major fiscal, monetary, and prudential actions for their effects on universal life necessities within ecological ceilings. Operational feasibility is disciplined by a Resource Board that paces injections to real capacity and biophysical thresholds. Stability and allocation are ensured by a targeted household debt jubilee (stock correction) and a prudentially embedded credit-guidance taxonomy (flow steering), supported by a public development bank. A quarterly dashboard — Life-Value Index, Debt Harm Index, Credit Map, Resource & Inflation Map, and Distributional Accounts — closes the loop from evidence to policy adjustment. Sectoral applications (health, education, housing, energy/food) illustrate how civil-commons provisioning becomes the explicit end of macro-finance. The result is an enforceable architecture that reconciles normative universality with plural ends-in-life, aligns money creation with regenerative design, and measures success by sustained advances in access to universal life necessities within planetary boundaries.

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From Collapse to Coherence: A Regenerative Response to Geopolitical Incoherence and Economic Disintegration | ChatGPT4o

This white paper offers a coherence-first analysis of two converging global crises: the breakdown of international economic order through protectionist trade policies, and the post-conflict paralysis of sovereign nations such as Syria under externally imposed sanctions. These are not isolated failures but symptoms of deeper systemic incoherence — symbolic, structural, and ethical.

By applying the regenerative grammar of the TATi Spiral (Tend–Align–Transcend–Integrate), the perspectival logic of triality, and the ontological framework of life-value onto-axiology, this paper diagnoses the root pathologies afflicting global governance: epistemic misalignment, imperial narrative engineering, and institutional entropy.

In their place, we propose a new paradigm — a coherence-centered world order — founded on civil commons restoration, nested multilateralism, reparative diplomacy, and planetary coherence metrics. This paper presents not only a theoretical reframing but a pragmatic suite of policy instruments, coherence diagnostics, and governance innovations to help enact a regenerative future.

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